Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSSF-SD------VLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLFS----EMVKDYSSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFM-LYLNFLVSIIFIVLSALPIIVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKLEDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKVLGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFVDAEHDNNGLYTSSIDEIHMKDVVYSITPENKLSIDFSFKSPF--RVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLS-------HGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKI-DILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNL---GI-SFIEVSHHYDLND-KRYTDIYKLENGTLFKIK 4MYC Chain:C ((111-652)) -----------VLIALGLLISAKILNVQVPFFFKQTIDSMNIAWDDPTVALPAAIGLTILCYGVARFGSVLFGELRNAVFAKVAQNAIRTVSLQTF-QHLMKLDLGWHLSRQTGGLTRAMDRGTKGISQVLTAMVFHIIPISFEISVVCGILTYQFGASFAAITFSTMLLYSIFTIKTTAWRTHFRRDANKADNKAASVALDSLINFEAVKYFNNEKYLADKYNGSLMNYRDSQIKVSQSLAFLNSGQNLIFTTALTAMMYMGCTGVIGGN-LTVGDLVLINQLVFQLSVPLNFLGSVYRDLKQSLIDMETLFKLRKNEVKIKNAER-PLMLPENVPYDITFENVTFGYHPDRKILKNASFTIPAGWKTAIVGSSGSGKSTILKLVFRFYDPESGR-ILINGRDIKEYDIDALRKVIGVVPQDTPLFNDTIWENVKFGRI-DATDEEVITVVEKAQLAPLIKKLPQGFDTIVGERGLMISGGEKQRLAIARVLLKNARIMFFDEATSALDTHTEQALLRTIRDNFTSGSRTSVYIAHRLR--TIADADKIIVLDNGRVRE--

General information: TITO was launched using: RESULT: Template: 4MYC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1899 3207 1.69 6.23 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain C : 0.71 3D Compatibility (PKB) : 1.69 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.395

(partial model without unconserved sides chains): PDB file : Tito_4MYC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MYC-query.scw PDB file : Tito_Scwrl_4MYC.pdb: