Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVAQAIRNIISPKSVIAQYQKIDFSNKGTIPIRHLNIGFDGKEIDIEFYVNNQFATLFFATLSVFLTYGEDLVIETARHHREFIQDPILKQRVTSLIGQEAIHSKLHNEFNDAIKELEYPVDLYRFLGENFFKYVFLKFPQPLKLSLMAGIEHFTAVLAEYMMKHEKNFYYTDDAKSRALWMWHMLEESEHKDIAYDVYQILNGNYPLRATGFLMAFITILGLIPTATLLVPVLRKPKELLTRKFWKDARRGVNLIFSPKDGVFGSTIGQIFDYLRPNFHPNDHDTTQYLEYYKNKLLNEGGAIAPYFVKEFTPPVRAVS 4ETR Chain:B ((19-147)) --------------------------------------------------------------------TSKDGEAGFHACAEDLRDPQLKAAMLEQSRDCAAAADE---LERIVLELGGKP------------------DEEAVLNECERGEDVAKHRYQAALE-----K-SLPAEIHQVIERQYQGVLRHHDRVRALRD------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4ETR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 340 -20669 -60.79 -196.84 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.51 3D Compatibility (PKB) : -60.79 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.51 QMean score : 0.332

(partial model without unconserved sides chains): PDB file : Tito_4ETR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ETR-query.scw PDB file : Tito_Scwrl_4ETR.pdb: