Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHLNSSIDKKMTTLNILFKTTSLCLAMALLVGCNDNDDNDSSTPAPRSNQTVNILAFNDFHGNLEPPKRYVEAANPNDASQTVRIPVGGVSYFADAIKK-LKAQNPNNVVVSAGDLISASPLTSSLFLDEPTIEVMNDIQIDFNAVGNHEFDRGTDELRRLQNGGCQQYTSTAPCQINKNFSGAKFNFLAANVAMKNDTSKTIFPAYKVKTYGGIPVAFIGLTLKATPSIVSAAGIKDVEFRDEADTVNALIPELQK-QGIEAIVVVVHEGAAPSTKLNQKTCDGLSGPILGILDRLNPA--VDIVVSGHTHQSYIC---------DYATKNPAKP-----FLLTSAGQYGTLITDIKVGLDGKTGDIIKKDAKQIPVQSEA----YT----SGTTTVSLTDLYQKFSKTPSIEAILDKYRQAVTTISGRVVGTSTAVVSRTQVESGESPLGDMIADAQQAAALQASNQGSDFTLMNPGGVRADLLINSSNQITFGDIFAVQPFGNSIVTLSLTGKQIRDVLEQQWSGANANSPRILQPSKELSYQYAANTSVSP--RASNIMVAGSPLVDTKVYRVTVNSFLADGGDNFTVLKEGQNRVGGGQ-DIDALESYVAQNSKDSPLIIPATTRIKVIK 1HP1 Chain:A ((37-502)) --------------------------------------------------------------------------------------------LVDGIRKEVAAEGGSVLLLSGGDINTGVP-ESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQE-------------------KWAKFPLLSANIYQKS-TGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGE------HGSNAPGDVEMARALPAGSLAMIVGGHS-QDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVG--RADFEFRNGEMKMVNYQLIPVNLKKKRVLYTPEIAENQQMISLLSPFQNKGKA--------QLEVKIGETNGRLEG------DRDKVRFVQTNMGRLI------LAAQMDRTGADFAVMSGGGIRDSI---EAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYL---------TAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYI---QKSSPL------------

General information: TITO was launched using: RESULT: Template: 1HP1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2342 52133 22.26 119.30 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 22.26 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.437

(partial model without unconserved sides chains): PDB file : Tito_1HP1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HP1-query.scw PDB file : Tito_Scwrl_1HP1.pdb: