Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSMSPSSSGHVNMMKGQPFHVKYREIIRRMSFLIGALLVFRLGAHIPVPGINNAALENLFHANQGTILGLFNMFSGGALERMSILALGIMPYISASIIVQL--------MSTVIPSLEALKKEGEQGKRKINQYTRQGTLLLAVVQAVGMC-AGLIGQGITLSSGLAFYIPAVTSLVAGTMFLMWLGEQITERGIGNGISMIIFAGIVAG-----------LPKLIMQSVSSVDNGQ--TSLIGLVIFGLLSLGVLAAIVFIEKAQRRIPVNYAQKQQGRRIFTAQQTHLPLKINMAGVIPAIFASSLLLFPASLGQWVGSADPNAGLI-------KRSLQDLALVLSP--------GQPLYLVLFGALIIFFC-----YFYTALVFSPKEVSENLKRSGAYVPGIRPGEQTARYLDHILNR----LTFIGAIYIAVICLMPMILQSSFGIPFYLGGTSLLIVVVVVMDFMAQLQAHLTFHQYDNQTLMRKTTAHPKG 3BO1 Chain:A ((25-427)) -------------------KLKWTGIVLVLYFIMGCIDVYTAGAQIP-------AIFEFWQTITASRIG-------------TLITLGIGPIVTAGIIMQLLVGSGIIQMDLSIPENRALF----QGCQKLL------SIIMCFVEAVLFVGAGAFG---ILTPLLAFLV--IIQIAFGSIILIYLDEIVSKYGIGSGIGLFIAAGVSQTIFVGALGPEGYLWKFLNSLIQGVPNIEYIAPIIGTIIVFLM-------VVYAECMRRRIVVNYAKRQQGRRVYAAQSTHLPLKVVYVSNIPVILAAALF---ANIQLW-GLALYRMGIPILGHYEGGRAVDGIAYYLSTPYGLSSVISDPIHAIVYMIAMIITCVMFGIFWVETTGLDPKSMAKRIKKSGAFVPGIRPGEQTAKYIEHRLKRYIPPLTVMSSAFVGFLATIANFI-GALG-----GGTGVLLTVSIVYRMYEQL------------------------

General information: TITO was launched using: RESULT: Template: 3BO1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1436 -194446 -135.41 -544.67 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -135.41 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.275

(partial model without unconserved sides chains): PDB file : Tito_3BO1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BO1-query.scw PDB file : Tito_Scwrl_3BO1.pdb: