Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGDPQGVIRHYVVCSTPQS--QYYLAEKHLFSTIPELINYH 3S9K Chain:A ((11-94)) WYNKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENPCIKHYHIKETNDSPKRYYVAEKYVFDSIPLLIQYH

General information: TITO was launched using: RESULT: Template: 3S9K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 239 -15899 -66.52 -193.89 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -66.52 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.552

(partial model without unconserved sides chains): PDB file : Tito_3S9K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3S9K-query.scw PDB file : Tito_Scwrl_3S9K.pdb: