Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDASDFLEA-DIAIVATYTYGDG--ELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAVDDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG 1J8Q Chain:A ((1-126)) -AKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFDLVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSYEYFCGAVDAIEEKLKNLGAEIVQDGLRID-----------------------

General information: TITO was launched using: RESULT: Template: 1J8Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 646 -19917 -30.83 -161.92 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -30.83 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.561

(partial model without unconserved sides chains): PDB file : Tito_1J8Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1J8Q-query.scw PDB file : Tito_Scwrl_1J8Q.pdb: