Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKAITDATFEQE--TKDGLVLVDFWATWCGPCRMQGPILDKLSEELSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTVEQIKAIIAELS 2L59 Chain:A ((12-109)) ----VTDASFATDVLSSNKPVLVDFWATWCGPCKMVAPVLEEIATERATD-LTVAKLDVDTNPETARNFQVVSIPTLILFKDGQPVKRIVG---AKGKAALLRELS

General information: TITO was launched using: RESULT: Template: 2L59.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 414 12486 30.16 130.06 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : 30.16 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.695

(partial model without unconserved sides chains): PDB file : Tito_2L59.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2L59-query.scw PDB file : Tito_Scwrl_2L59.pdb: