Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLQFIASCPQHGVLDHPPNECHITQEYVAALLFKQLGNYGFDA--QHIVHEHE----KVEVSIDNHLL-PLSITCQQTDHDGHLMCEISANPDEEQDWFEKIETQSIIRQLAQAVENSLKADHSFSAFEWKS 3H3R Chain:A ((28-116)) -------------------------VEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHVVETLA--------------------

General information: TITO was launched using: RESULT: Template: 3H3R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 136 7978 58.66 97.29 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 58.66 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.125

(partial model without unconserved sides chains): PDB file : Tito_3H3R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H3R-query.scw PDB file : Tito_Scwrl_3H3R.pdb: