Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLDLFSPEPCSNLLPYDGVVQDYGCILTVEEAEQYFHYLYHHLAWRHD---EAKLYGKHFITPRKVAWYGDEHYRYKYSGVFRDSLPWDKALAQLKQQVEQILSEKFNSCLANLYEDGTQGMAWHSDSDVSLARTTTIASLSFGAMRKFSFRHIQTKEK--------VEMWLQPGQLIVMRGETQQYWQHRLNRSTKILQPRINLTFHQFKFS 3BTX Chain:A ((9-202)) -----------------EGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKI---

General information: TITO was launched using: RESULT: Template: 3BTX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 758 14896 19.65 81.40 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 19.65 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.300

(partial model without unconserved sides chains): PDB file : Tito_3BTX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3BTX-query.scw PDB file : Tito_Scwrl_3BTX.pdb: