Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKMQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIYIASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILIDDVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEILVEMQELDGQDRIMILKEED 4P83 Chain:A ((5-178)) ----KAVIMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGAPVPVGEIDITL---------DEPLVKGTNVPFPVTERNVILVDDVLFTGRTVRAGMDAVMDLGRPARIQLAVLVDRGHRELPIRADFVGKNVPTSRSELIVVELDEVDQNDQVSI-----

General information: TITO was launched using: RESULT: Template: 4P83.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 845 -134236 -158.86 -823.53 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.91 3D Compatibility (PKB) : -158.86 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.627

(partial model without unconserved sides chains): PDB file : Tito_4P83.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4P83-query.scw PDB file : Tito_Scwrl_4P83.pdb: