Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLKRATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDKRIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQEDTFDSLEEKIHRVEHRIYPEVISEIIENGGYLK 1C2T Chain:A ((1-182)) MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVIS----------

General information: TITO was launched using: RESULT: Template: 1C2T.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 929 -135695 -146.07 -745.58 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -146.07 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.559

(partial model without unconserved sides chains): PDB file : Tito_1C2T.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1C2T-query.scw PDB file : Tito_Scwrl_1C2T.pdb: