Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNNTTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLILAAGFTW-EEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPGAGSVISFVETAT-QTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRNNIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF 4JDP Chain:A ((26-260)) -DKKGYIIDIDGVIGKSVTPIPEGVEGVKKLKELGKKIIFVSNNSTRSRRILLERLRS-FGLEVGEDEILVATYATARFIAREKPNAKVFTTGEEGLIEELRLAGLEIVDYDEAEYLVVGSNRKINFELMTKALRACLRGIRYIATNPDRIFPAEDGPIPGTGMIIGALYWMTGREPDVVVGKPSEVIMREALDILGLDAKDVAVVGDQIDVDVAAGKAIGAETVLVLTGVTTRENL-------------------

General information: TITO was launched using: RESULT: Template: 4JDP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1337 -56115 -41.97 -240.84 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -41.97 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.655

(partial model without unconserved sides chains): PDB file : Tito_4JDP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JDP-query.scw PDB file : Tito_Scwrl_4JDP.pdb: