Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRASTVTIKTEQDLEKLRVSGRLAAQVLEMIGEYVKPGVTTEYLDNICNDYIVNTLKVIPANVGYHGFTKTICISVNEVVCHGIPSQNKILKDGDIINIDVAIIKDGYFGDTSRMYYVGNVNPHAKKLVETTYEAMVAGIHAVKPGATLGDIGYAIQSVAHREGYSIVREYCGHGIGKVYHEQPNILHYGQRGQGLVLKKGMVFTIEPMVNAGKPQVKE-LNDGWTVITQDHSLSAQWEHMVAVTDTGFELLTPWPEGVGNYPEI 3MX6 Chain:B ((3-260)) --GSMIKIHTEKDFIKMRAAGKLAAETLDFITDHVKPNVTTNSLNDLCHNFI-TSHNAIPAPLNYKGFPKSICTSINHVVCHGIPNDK-PLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQVTYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDYTGHGIGRVFHDKPSILNYGRNGTGLTLKEGMFFTVEPMINAGNYDTILSKLDGWTVTTRDKSLSAQFEHTIGVTKDGFEIFTLSPKKLDYP---

General information: TITO was launched using: RESULT: Template: 3MX6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1541 -140304 -91.05 -545.93 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain B : 0.89 3D Compatibility (PKB) : -91.05 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.612

(partial model without unconserved sides chains): PDB file : Tito_3MX6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3MX6-query.scw PDB file : Tito_Scwrl_3MX6.pdb: