Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGSGKSTLAKTINGLLLP---ESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDDVAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPDIIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGELVREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSVLNK 5JSZ Chain:A ((21-297)) -DNIISFDHVTFTYPDS-PRPALSDLSFAIERGSWTALIGHNGSGKSTVSKLINGLLAPDDLDKSSITVDGVKLGADTVWEVREKVGIVFQNPDNQFVGATVSDDVAFGLENRAVPRPEMLKIVAQAVADVGMADYADSEPSNLSGGQKQRVAIAGILAVKPQVIILDESTSMLDPEGKEQILDLVRKIKEDNNLTVISITHDLEEAAGADQVLVLDDGQLLDQGKPEEIFPKVEMLKRIGLDIPFVYRLKQLLKERGIVLPDEIDDDEKLVQSLWQLN---

General information: TITO was launched using: RESULT: Template: 5JSZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1423 31179 21.91 113.79 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : 21.91 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.501

(partial model without unconserved sides chains): PDB file : Tito_5JSZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JSZ-query.scw PDB file : Tito_Scwrl_5JSZ.pdb: