Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIV-GYLKEQFDYL---KEKYGVRLVFNDKYADYNNFYSLYLVKEEL--ANSYVIDADNYLFKNMFRNDLTRS-------TYFSVYREDCTNEWFLVYGDDYKVQDIIVDS---KAGRILSGVSFWDAPTAEKIVSF------------IDKAYASGEFVDLY-------WDNM-VKDNIKELDVYVEELEGNSIYEIDSVQDYRKLEEILKNEN-------------------------- 1FXO Chain:A ((2-293)) KRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTETVY

General information: TITO was launched using: RESULT: Template: 1FXO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1238 -883 -0.71 -3.86 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -0.71 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.455

(partial model without unconserved sides chains): PDB file : Tito_1FXO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FXO-query.scw PDB file : Tito_Scwrl_1FXO.pdb: