Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLEDKVVLVTGSSGGLGAQICYEAAKQGA---IVISCARRMAFVEGVRDECRRL--SGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTFDLGKACDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKFAVLGFSNALRLELKPLGVAVTTVNPGPIETDFFDKADPSG--SY---L---------------EKVGQIVLEPAKLAKMIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK 1JTV Chain:A ((2-249)) ----RTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVT--EGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHT-------GSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEVFLTALRAPKP---------------------------------

General information: TITO was launched using: RESULT: Template: 1JTV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1003 -50703 -50.55 -234.74 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -50.55 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_1JTV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JTV-query.scw PDB file : Tito_Scwrl_1JTV.pdb: