Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRGMLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRDLVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFYKD-DLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLIT-GEETTAAER-QSTFNEMIEVGLETAIAE 3UAW Chain:A ((2-234)) -SVHIEAKQGEIAESILLPGDPLRAKYIAETFLEDVTCYNNVRGMLGFTGTYKGKRVSVQGTGMGVPSISIYVNELIQSYGVKNLIRVGTCGAIQKDVKVRDVIIAMTACTDSNMNRLTFPGFDFAPAANFDLLKKAYDAGTEKGLHVRVGNVLTADVFYRESMD-MVKKLGDYGVLAVEMETTALYTLAAKYGVNALSVLTVSDHIFTGE--ETTSEERQTTFNEMIEIALDAAIQ-

General information: TITO was launched using: RESULT: Template: 3UAW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1425 -129226 -90.68 -561.85 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.91 3D Compatibility (PKB) : -90.68 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.523

(partial model without unconserved sides chains): PDB file : Tito_3UAW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UAW-query.scw PDB file : Tito_Scwrl_3UAW.pdb: