Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINKKPRIPSPVQIPEHLSFLQGFRDYLVAQ-TVSPHTRNAYLSDLIQCSEIHKKN--RLPDWTSDDISDVLIELTKVGKSPRSIARCLSALRQFYKSLREQKLRSDNPVATH----HSPKI---G---R-ALPKDLSEEDVEALIQAPDITTALGLRDRAMFEVLYACGLRVSELLNLRLELINLKQ-GYLRI---TGKG---NKERLVPLGQYACDWVERYLNEARPQLYKSSTDYLFLTQHG---------GIMSRQNFWYAIKR-------YALQANIQ-AELSPHTLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVAQVRMQQLHEKHHPRG 1CRX Chain:A ((4-319)) -------------------VRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRRIRKENVDAGERAKQALAFERTDFDQVRSLMENSDR--CQDIRNLAFLGIAYNTLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTKLVERWISVSGVA--DDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNIVMNYIRNLDSETGAMVRL-----

General information: TITO was launched using: RESULT: Template: 1CRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1113 3462 3.11 12.45 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 3.11 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.432

(partial model without unconserved sides chains): PDB file : Tito_1CRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CRX-query.scw PDB file : Tito_Scwrl_1CRX.pdb: