Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTPGSVFFDQQFSFHDGESGEKLFVILGWD-------NGIAIVAKTTSQQHGRGTTFGCQPKDRFHNFYLPQNSCYFRKCTWVCLDEFYELNAVEVLQKRFSGLINPVCNLTNEMLRKLQDCALESDDLSGRQESIIRSSLV 5WYG Chain:A ((8-118)) PRRGDLWLVS-LG------KHRPAVVVSVDELLTGIDDELVVVVPVSSSRSRTP--------LR---PPVAP-SEGVAADSVAVCRGVRAVARARLV--------ERLGALKPATMRAIENALTLILGLP------------

General information: TITO was launched using: RESULT: Template: 5WYG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 472 -25331 -53.67 -263.86 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -53.67 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_5WYG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5WYG-query.scw PDB file : Tito_Scwrl_5WYG.pdb: