Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSQPTTPSQSVIPAWVDS--SLLQGMLRGIERESLRMQSNGFLSQELHPKALGSALTHPKITTDYSEALMEFITSPQPTIGDALHELT---DIHAVVHRHLENGEKLWPLSMPCTLDDNEERIRLAQYGTSNIGRFKTLYRRGLGIRYGRRMQTISGVHYNLSFPDSLFSALQAHETDEKLKALSLQDYRSHRYFGLIRNFIRLTPLVMFLVGASPSVCHCFLTGHEHHLLPLIK---GSYYLPYATALRMGRLGYQNSAQKSLGIHYNNLTDYLDGLQKAVHSPYPPFSRLGLNDASGEPLQINDHVLQIENEYYSLVRPKQVPQAGETPSQALKNRGVGYVELRAVDVNPYSAIGVNETTAGFLEALALYCLLSDSPELLCPEQDLIEKNQTEVVNRGRAPNAT--ITDLNGSYHIEDWARQHISKMQDCARLLDQTYATDLYSSALAVMQERIDEVDETLSAHVIDDTLKHGGTWSFGSHMAQLHAETYEKHEISAETLQYFEQLAVQSLQQQEQLEQDSQISFDQYLEQYR 1VA6 Chain:B ((3-515)) ------PDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFIT---PVDGDIEHMLTFMRDLHRYTARNMGD-ERMWPLSMPSYIAEGQD-IELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW---QAKSG------ADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAISSSFL----TSL-PFEKTESGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGI-EKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDT--T---GKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTEPFAVWLE---

General information: TITO was launched using: RESULT: Template: 1VA6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2707 12352 4.56 25.16 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : 4.56 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_1VA6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VA6-query.scw PDB file : Tito_Scwrl_1VA6.pdb: