Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNPRSLEEEKYDMSGARLALILCVTKAREGSEEDLDALEHMFRQLRFESTMKRDPTAEQFQEELEKFQQAIDSREDPVSCAFVVLMAHGREGFLKGEDG--EMVKLENLFEALNNKNCQALRAKPKVYIIQACRGEQRDPG-ETVGGDEIVMVIKDSPQTIPTYTDALHVYSTVEGYIAYRHDQKGSCFIQTLVDVFTKR--KGHILELLTEVTRRMA----EAELVQEGKARKTNPEIQSTLRKRLYLQ 4QU9 Chain:A ((63-275)) ---------------------------SRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVC---VLLSHGEEGIIAGTNGPVDLKKITNFFRG---DRCRSLTGKPKLFIIQACRGTELDCGIE---------------HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYF-

General information: TITO was launched using: RESULT: Template: 4QU9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 875 -1103 -1.26 -5.71 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -1.26 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.555

(partial model without unconserved sides chains): PDB file : Tito_4QU9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QU9-query.scw PDB file : Tito_Scwrl_4QU9.pdb: