Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE 2JX5 Chain:A ((1-69)) MLVIVRLQDQTLPFELPAGARASQLSNLLSS------SGMAFSLHTQGRVLSEAAELN---------------DKMVIDAFVPADGAGLE

General information: TITO was launched using: RESULT: Template: 2JX5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 240 -40607 -169.20 -588.51 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -169.20 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.245

(partial model without unconserved sides chains): PDB file : Tito_2JX5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JX5-query.scw PDB file : Tito_Scwrl_2JX5.pdb: