Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALLAEFYSKEGNMNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDTVKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDILPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVYRLKLSGTFVYLPEN--NMLGFIHPSERY---AEPRLGQVLDARVIGFREVDRTLNLSLKPRSFEMLE---------NDAQMILTYLE-SNGGFMTLNDKSSPDDIKATFGISKGQFKKAL--GGLMKAGKIKQDQFGTELI 2A19 Chain:A ((13-157)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------PEIDDIVMVNVQQIAEMGAYVKLL-EYDNIEGMILLS---SIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGI------------

General information: TITO was launched using: RESULT: Template: 2A19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 412 -26302 -63.84 -219.18 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -63.84 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.289

(partial model without unconserved sides chains): PDB file : Tito_2A19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2A19-query.scw PDB file : Tito_Scwrl_2A19.pdb: