Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRIIPVYIFQQVNVLLV-------SLYLL-KFLCIG---ELTILQILYGSSLI-SFLWMYGQRKQAHKVNMKS--RMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQIPWFSFLLF-------LINASMVEEFLYREILCNLVRKLDIRVALTSVLFALAHHTGTILAW-CLYVSLGMFLGMVRYKSDLWGSMG-LHLVWNLLVYSLLLF----------------------- 5UC2 Chain:A ((5-245)) AVRLVPHRAIYDLTLDRADEKSGISGLTGRMVYEFNGSACEGYTTNFRFVTRVDMDEQPQRVTDQQTTTFEDADGKDFRFVNKTFVDKELVKEVRGDAKLEDGKTVVKLSKPKENTLDLKGTQFPTRHMEELIGKAEAGQKFYQTTLFDASEDADRVVATTVVVGKQQAVPDDETKVMGKFSKDQVWPVTIAYFDDKEQQDGMPIYRINFKLYRNGITRDLTMDYGDFSMRGKLVKLDIYD

General information: TITO was launched using: RESULT: Template: 5UC2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 826 -38926 -47.13 -199.62 target 2D structure prediction score : 0.11 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -47.13 2D Compatibility (Sec. Struct. Predict.) : 0.11 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.014

(partial model without unconserved sides chains): PDB file : Tito_5UC2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5UC2-query.scw PDB file : Tito_Scwrl_5UC2.pdb: