Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIEIRTDKNIHNSERLITYVRAELTQEFQRHSERITHFSVHFSDENGDKGGDKDIHCMIEARPSGLKPVAVHHKA-GNIDASIHGAIEKLKRSLEHTFEKKEHPRGGQPEFIDDEV 3UEB Chain:E ((31-106)) -------------QETIIDYVFDHLTR------SEVKDIEVTMRINRE-----ETLDLEIEVYLEV-PIF-VKVDVDKLIDEAVERAYEIVERKLREIANER---------------

General information: TITO was launched using: RESULT: Template: 3UEB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 196 -30581 -156.02 -407.74 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain E : 0.72 3D Compatibility (PKB) : -156.02 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.341

(partial model without unconserved sides chains): PDB file : Tito_3UEB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UEB-query.scw PDB file : Tito_Scwrl_3UEB.pdb: