Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTDITLKTPVEMRNV-----QLKVYDNTDNSILI-DTQVASLTSYDIKLPSTKLNRLYRIEVTTQGSSQVFDPTKSEYQNISGVYH----------AFITPSSISNKTQLISPSS------EAIYQRAVIRSGQLPNETIIPTRIEQLHVDLASQDVY-RSLLNAFKDT---NIPSLSPASTLTILNLLKYSTTKPSTYVDSYLCFGYLQYWSSIHNTNSPYQ--------------DLTQSLATDLKDGYLDGKK---------LIGDK-------TSFTPIFT--SAPDNIDPAKNTLLD-IAANQKVTRDYFATNLRAATFKL-ADLQDQSH-----LDPIGYDLLDKKQYSGII-----------PAGNTSEFFRIDGA-----GDYRRAVGFSGITATCNGSAYP---CKQGLTSINISDPKLP-ATDYLVGHYEDSTTGCQL--NFRANGQI--ELIKGSQSYRSALSADSTDKLLQTDAASYSYLLNSSSSEPNNSTQQYNFIQLHIK------ANKIVSAQAGLDSRKAPDV--LQTTQLEYSFS------------------------------------------------------------ 5AKP Chain:B ((18-638)) ---VCAREPIHIPGLIQPYGVLLVIDPADGRIVQASTTAADL----LGVPMAALLGMPYTQVLTLPEAQPFAVDDQPQHLMHAEVRFPQRATPPASAWVAAWHLYPQQWLVEMEPRDARLLDVTLREAMPLLRSVERDPGIAEAAVRVAKGLRSLIGFDRVMIYRFDEEWNGDIIAEARKPELEAYLGLHYPASDIPAQARALYLRNRVRQIADVGYQPSPIQPTVHPQLGTPVDLSDVSLRSVSPVHLEYLANMGVTATLVASIVVNDALWGLISCHHYSPHFTNHAMRDVTDAVARTLAGRIGALQAVARARLESVLLTVREKLITDFNDAEHMTVELLDDMAPDLMDVVDADGVAIFHGNDISRHGTTPDVAALRRIRDHIESEHHEALREDAVGALHVDAIGEVFPELADLAPLAAGFIFVPLMPQSRSALLWTRREQIQQIKWAGNPRKSFDLWQQTVRGRARRWSPLHLESARSLRVLIELMERKRFQQDFTLLEASLSRLRDGVAIIERGTANAAHRLLFVNTAFADVCGSDVAELIGRELQTLYASDAPRANVELLQDALRNGRAAYVTLPLQVSDGAPVYRQFHLEPLPSPSGVTAHWLLQLRD

General information: TITO was launched using: RESULT: Template: 5AKP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2151 24275 11.29 54.06 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain B : 0.64 3D Compatibility (PKB) : 11.29 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.067

(partial model without unconserved sides chains): PDB file : Tito_5AKP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5AKP-query.scw PDB file : Tito_Scwrl_5AKP.pdb: