Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGILLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITSDRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVSLNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHY-LEDIRLRLSAEIG-RGLTLLEAKGGYNR---KSKEVLLIVVTDHEFSRMKPLIEEID-----PSAFVIVSSVAEVMGRGFTYHPIE 3T9Z Chain:B ((4-103)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VVAVIRPEKLECVKKALEE-RGFVGMTVTEVKGRG--VDLLQKTKVEVVVSDDAVDEVVEAIVSSARTGKFGDGRIFVIPVEKSVKIR-------

General information: TITO was launched using: RESULT: Template: 3T9Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 295 -3160 -10.71 -42.13 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.43 3D Compatibility (PKB) : -10.71 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.43 QMean score : 0.403

(partial model without unconserved sides chains): PDB file : Tito_3T9Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3T9Z-query.scw PDB file : Tito_Scwrl_3T9Z.pdb: