Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLKAIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHRDEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAVRAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIASAVAFAIETPDRMSVSNMIIRPTTQEV 3P19 Chain:C ((16-249)) -----KKLVVITGASSGIGEAIARRFSEEGHPLLLLARRVERLKALN----LPNTLCAQVDVTDKYTFDTAITRAEKIYGPADAIVNNAGMMLLGQIDTQEANEWQRMFDVNVLGLLNGMQAVLAPMKARNCGTIINISSIAGKKTFPDHAAYCGTKFAVHAISENVREEVAASNVRVMTIAPSAVKTELLS----------------GGVLAADDVARAVLFAYQQPQNVCIREIALAPT----

General information: TITO was launched using: RESULT: Template: 3P19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1182 -132257 -111.89 -612.30 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain C : 0.81 3D Compatibility (PKB) : -111.89 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.578

(partial model without unconserved sides chains): PDB file : Tito_3P19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P19-query.scw PDB file : Tito_Scwrl_3P19.pdb: