Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVAAQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENF--LTHAKEGY-YNGITFHRVIDGFMVQTGD-PKGDGTGGQSIWHDKDKTKDKGTGFKNEITPYLYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLDGKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS 3RDD Chain:A ((37-177)) ----------------------------------------------------------------------------------GRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEK---------FEDENFILKHTGPGILSMANAG-PNTNGSQFFICTAKTEW------------------------LDGKHVVFGKVKEGMNIVEAMERF-GSRNGKTSKKITI-------------

General information: TITO was launched using: RESULT: Template: 3RDD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 690 35093 50.86 256.15 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 50.86 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.539

(partial model without unconserved sides chains): PDB file : Tito_3RDD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RDD-query.scw PDB file : Tito_Scwrl_3RDD.pdb: