Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYKLDLKLG-SAELEIFGIANAPQRPNYPEACGLRHLAFKV---DDIEETIAELQSLGIESEPIREDTFTGKKMTFFFDPDGLPLELHE 3E5D Chain:A ((2-127)) ---MKIEHVALWTTNLEQMKQFYVTYFGATANDLYENKTKGFNSYFLSFEDGARLEIMSRTDVTGK-TTGENLGWAHIAISTGTKEAVDELTEKLRQDGFAIAGEPRMTGDGYYESVVLDPEGNRIEITW

General information: TITO was launched using: RESULT: Template: 3E5D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 434 -17076 -39.35 -139.97 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -39.35 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_3E5D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3E5D-query.scw PDB file : Tito_Scwrl_3E5D.pdb: