Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKQTVQLEIISVNQTKTKIELVISQIEQQIKNRSLTPGTRLPSVRKLAKDLGFSVSTIVEAYERLIALGKIESRSGSGFYVVAPLAPLALNELGPKLDRSIDPLWISRQSLEAEPNAFKPGCGWLPNDWMPLESIRKALRSATRSEDDSLLGYSSPLGLSALRD----LLARRAQSKGIEANLNQVLLTDSGTQAIDLVCRFLLKPDDVVLIDDPCYFNFHALLKVHQVKVVGIPYTPNGPDLEAFKEAIEGYNPR--------LYITNSGIHNPTGATLSLSTAHQLLKLIDQSNLIVIEDDIFSDFEY---TPAPRLAALDNLSRVIFIGSFSKTLSASIRCGYIIAKPEWIDQIADLK-----IATSFSHNGLSAKILHTALTDGSYRKHLDLLKVRLA---QAMQETIAKLKSIRIEPWIEPKAGIFVWCRLPEGVDAEKIAQFCLNRQVILAPGNAFSQAQSAGQFIRFNITQSNHDYIY---KTLAEALLQESLEKQV 1VP4 Chain:A ((41-424)) -----------------------------------------------------------------------------------------------------------------ADKDAISFGGGVPDPETFPRKELAEIAKEIIEKEYHYTLQYSTTEGDPVLKQQILKLLERMYGITGLDED--NLIFTVGSQQALDLIGKLFLDDESYCVLDDPAYLGAINAFRQYLANFVVVPLEDDGMDLNVLERKLSEFDKNGKIKQVKFIYVV-SNFHNPAGVTTSLEKRKALVEIAEKYDLFIVEDDPYGALRYEGETVDP-IFKIGGPERVVLLNTFSKVLAPGLRIGMVAGSKEFIRKIVQAKQSADLCSPAITHR-LAARYLERYDLLEQLKPTIELYRRKRTVMLNALEEYFSDIPGVK---WVKSEGGLFIWLTLPEGFDTWEMFEYAKRKKVFYVPGRVFKVYDEPSPSMRLSFCLPPDEKIVEGIKRLREVVLEYGKEKHL

General information: TITO was launched using: RESULT: Template: 1VP4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1979 -4077 -2.06 -11.39 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -2.06 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_1VP4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VP4-query.scw PDB file : Tito_Scwrl_1VP4.pdb: