Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTPGSVFFDQQFSFHDGE-SGEKLFVILGWD--N---GIAIVAKTTSQQHGRGTTFGCQPKDRFHNFYLPQNSCYFRKCTWVCLDEFYELNAV-EVLQKRFSGLINPVCNLTNEMLRKLQDCALESDDLSGRQESIIRSSLV 1M1F Chain:A ((1-107)) MERGEIWLVSLDPTAGHEQQGTRPVLIVTPAAFNRVTRLPVVVPVTS---FARTAG----------FAVSLDGVGIRTTGVVRCDQPRTIDMKARGG--------KRLERVPETIMNEVLGRLST-----------------

General information: TITO was launched using: RESULT: Template: 1M1F.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 432 -9006 -20.85 -92.84 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -20.85 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.373

(partial model without unconserved sides chains): PDB file : Tito_1M1F.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1M1F-query.scw PDB file : Tito_Scwrl_1M1F.pdb: