Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTLSMNYLQDARQHVLQQIRTACELAQREPE--TVQLLAVSKTHPSERLREMYAAGQRAFGENYLQEALDKIDALQDLDIEWHFIGHVQRNKTKHLAE--KFDWVHGVDRLIIAERLSNQRGDDQA---ALNICLQVNIDGQESKDGCAPEDVAELVAQMS---QLPKIKLRGL-MVIPAPDNTGAFADAKKLFDAVKVQHAHPEDWDTLSMG-M-SSDLEAAIAAGSTMVRVGTALFGARDYSQKG 1CT5 Chain:A ((2-245)) ---TGITYDEDRKTQLIAQYESVREVVNAEAKNVKILLLVVSKLKPASDIQILYDHGVREFGENYVQELIEKAKLLPD-DIKWHFIGGLQTNKCKDLAKVPNLYSVETIDSLKKAKKLNESRAKFQPDCNPILCNVQINTSHEDQKSGLNNEAEIFEVIDFFLSEECKYIKLNGLMTIGSWNRDFATLVEWKKKIDAKF--------GTSLKLSMGMSADFREAIRQGTAEVRIGTDIFG--------

General information: TITO was launched using: RESULT: Template: 1CT5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1001 53619 53.57 249.39 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : 53.57 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.497

(partial model without unconserved sides chains): PDB file : Tito_1CT5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CT5-query.scw PDB file : Tito_Scwrl_1CT5.pdb: