Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWCFKNGQPVETIPLLDRAFHYGDGCFTTIRVFQN-KIELKARHWERL-------KLACQKLSLVADFELIEQSLQRLQNQNLVLNGTLKIVISRGEGDRGYSLPK-HAADIYIWFYP-KALEQFQPDFIQCGVLNQALGLTMPSLVGLKSLNRLEQVLLKKEADQQGWVEALVTDVQGYIVEGVSSNCFIRLNDRWITPELRYNGVHGVMRAEILVRMQHYGIACEVRIIELDEVPQIQSLFFCNA---LHPMRVVTQISEQILESQACLNLFHTLNLNQIH 1A3G Chain:A ((24-270)) --------------VMSHALHYGTSVFEGIRCYDSHKGPVVFRHREHMQRLHDSAKIYRFPVSQSID-ELMEACRDVIRKNNLT-SAYIRPLIFVGDVGMGVNPPAGYSTDVIIAAFPW----QGIDAMVSS--WNRAAPNTIPTAAKAGG-NYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGI-----------------------

General information: TITO was launched using: RESULT: Template: 1A3G.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1080 -22566 -20.89 -100.74 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -20.89 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.388

(partial model without unconserved sides chains): PDB file : Tito_1A3G.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A3G-query.scw PDB file : Tito_Scwrl_1A3G.pdb: