Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGKISREESEQIVLIGSKTNGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHY 3EAC Chain:A ((82-156)) WFHGKITREQAER--LLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRI-MYHASKLSIDEEVYFENLMQLVEHY

General information: TITO was launched using: RESULT: Template: 3EAC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 259 -22136 -85.47 -299.14 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -85.47 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.716

(partial model without unconserved sides chains): PDB file : Tito_3EAC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EAC-query.scw PDB file : Tito_Scwrl_3EAC.pdb: