Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MALLAEFYSKEGNMNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDTVKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDILPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVYRLKLSGTFVYLPEN--NMLGFIHPSERY--------AEPRLGQVLDARVIGFREVDRTLNLSLKPRSFEMLEN---------DAQMILTYLE-SNGGFMTLNDKSSPDDIKATFGISKGQFKKAL--GGLMKAGKIKQDQFGTELI 1Q46 Chain:A ((13-157)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------PEIDDIVMVNVQQIAEMGAYVKLL-EYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGI------------

General information: TITO was launched using: RESULT: Template: 1Q46.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 435 -1096 -2.52 -8.91 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -2.52 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.281

(partial model without unconserved sides chains): PDB file : Tito_1Q46.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q46-query.scw PDB file : Tito_Scwrl_1Q46.pdb: