Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTANIMTTLKNQITDALKTSMRAKDMATVTVLRSLQAAIKQI---------EVDERIELDDAQVLAVIEKQIKQRKESIKAFEGAGRDDLASKEQAEAEVLSQFLPEAMTEEELDSLIEQTIAAQEATSMKDMGKVMNSLRPIIAGRADPAQVSAKIKAKLA 2O42 Chain:A ((57-138)) LSYNIVN-IKNTLTFALRDASPSVKLATLTLLASVIKKLNKIQHTDAAMFSEVIDGIVAEEQQVIGFIQKKCKYNTTYYNVRS-------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2O42.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 185 -9318 -50.37 -127.64 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -50.37 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.619

(partial model without unconserved sides chains): PDB file : Tito_2O42.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2O42-query.scw PDB file : Tito_Scwrl_2O42.pdb: