Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKSVTQENSVPVIGQRFRGFLPVVVDVETAGFNAQTDALLEIACIPIVYDAQGQFVPGPAFHAHINPFEGANLDRRSLDFIGIDPFNPMRIAMAEDERTALRRIFKSVNEVRKQQHCTHAVLVGHNAHFDLGFLQAAIARSGTKNQNPFHSFSVMDTVTLSAVMFGQTVLAKACIQAGIEFDGKEAHSALYDTQKTAELFCYILNKLSPYLLDSLVAAS 3V9W Chain:A ((33-221)) ----------------RFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSGYE--ALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLK-RNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRW------------

General information: TITO was launched using: RESULT: Template: 3V9W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 967 -132456 -136.98 -700.82 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -136.98 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_3V9W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V9W-query.scw PDB file : Tito_Scwrl_3V9W.pdb: