Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTEHFDLANPV------------TKVDDIPDYEMYSQTIDSLNKRF--GNRVLKGIKIGYIASEKDRIIDYLADK--DYDLKLLSVHHNG-QF---DYL--DDEVK------DMDPAIVIPQYFAQLSEALVV--IE--ADVFAHFDYGFRVFGLSVAE---F-KQYEAQFLPILDQVIKNKLAFELNAKSAYLYD-N-LALYEYVIDLCLSRGGTLF 3DCP Chain:B ((36-254)) SIVEHAPLSSEFMKNTAGDKEAVTTASMAMSDLPYYFKKMNHIKKKYASDLLIHIGFEVDYLIGYEDFTRDFLNEYGPQTDDGVLSLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLAYLEGVKQSIEADLGLFKPRRMGHISLCQKFQQFFGEDTSDFSEEVMEKFRVILALVKKRDYELDFNTAGLFKPLCGETYPPKKIVTLASELQIPFV

General information: TITO was launched using: RESULT: Template: 3DCP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 814 18748 23.03 103.58 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.65 3D Compatibility (PKB) : 23.03 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.378

(partial model without unconserved sides chains): PDB file : Tito_3DCP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DCP-query.scw PDB file : Tito_Scwrl_3DCP.pdb: