Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTD 2XMW Chain:A ((8-41)) ----QLEGMRCAACASSIERAIAKVPGVQSCQVNF-------

General information: TITO was launched using: RESULT: Template: 2XMW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 45 -17148 -381.06 -553.15 target 2D structure prediction score : 0.84 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -381.06 2D Compatibility (Sec. Struct. Predict.) : 0.84 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.778

(partial model without unconserved sides chains): PDB file : Tito_2XMW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XMW-query.scw PDB file : Tito_Scwrl_2XMW.pdb: