Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRYIDPNQPGSKVQFKSQYENFIGGEWVAPLKGEYFDNVSPVDGKAFTRIPRSSAEDIELALDAAHKAKASWNKYSPTTRSNILLKIADRLEANLEMLAVAETWDNGKAVRETLAADLPLAIDHFRYFAGCIRAQEGGISEIDEDTIAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNCVVIKPAEQTPVGILLVAELIQDI-LPPGVLNIVNGFGAEVGRPLATSPRIAKIAFTGSTQTGQMVMQYATENIIPVTLELGGKSPNLFFEDIMDKEDDFLEKTLEG--FAMFALNQGEVCTCPSRALVQESIADQFLELAVERVKRIKTGHPLDTETMIGAQASLQQQEKILRCINTGREEGAELLLGGSGRKE--VGDGFYVDPTIFKG-HNSMQVFQEEIFGPVLAVTTFKDFDDAIKIANDTMYGLGAGVWSRSAHISYRAGRAIEAGRVWTNCYNIYPAHAAFGGYKKSGIGRENHKMMLDHYQQTKNLLVSYSTKPMGFF 4O6R Chain:B ((10-485)) -----------------QTQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAFPAWSAMPAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKLQGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPLSTLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEASQGNLKRVQLELGGKGANIVFDDAN------LDAAINGAAWAIFH-NQGQACIAGSRLVLHERIADAFLERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPALANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTNDLSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVN---------

General information: TITO was launched using: RESULT: Template: 4O6R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2974 -109641 -36.87 -233.28 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -36.87 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.527

(partial model without unconserved sides chains): PDB file : Tito_4O6R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O6R-query.scw PDB file : Tito_Scwrl_4O6R.pdb: