Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQILGGNNMAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIELS--KKGY-YDGVIFHRVIPDFMIQGGDPT-GTGMGGESIYGESFEDEFSRELFNLRGALSMANSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHVLEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE 1YND Chain:B ((18-142)) ------------------------------GRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAK---------------------------TEWLDGKHVVFGKVKEGMNIVEAM------------------------

General information: TITO was launched using: RESULT: Template: 1YND.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 565 16594 29.37 137.14 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain B : 0.71 3D Compatibility (PKB) : 29.37 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.500

(partial model without unconserved sides chains): PDB file : Tito_1YND.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YND-query.scw PDB file : Tito_Scwrl_1YND.pdb: