Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPVIPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKAKKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGGVLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILMTKESETIEL 3C3P Chain:A ((5-210)) ---------IVDSRIGAYLDGLLPEADPVVAAMEQIARERNIPIVDRQTGRLLYLLARIKQPQLVVVPGDGLGCASWWFARAISISSRVVMIDPDRDNVEHARRMLHDNGLIDRVELQVGDPLGIA-AGQRDIDILFMDCDVFNGADVLERMNRCLAKNALLIAVNALRRG------------------ALREFNHHLSRRRDFFTTIVPVGNGVLLGYRLS-----

General information: TITO was launched using: RESULT: Template: 3C3P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1035 -152936 -147.76 -788.33 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -147.76 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.577

(partial model without unconserved sides chains): PDB file : Tito_3C3P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3C3P-query.scw PDB file : Tito_Scwrl_3C3P.pdb: