Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIERTLSIVKPDAVSKNHIGEIFARFEKAGLKIVATKMKHLSQADAEGFYAEHKERGFFGDLVAFMTSGPVVVSVLEGENAVLAHREILGATNPKEAAPGTIRADFAVSIDENAAHGSDSVASAEREIAYFFADNEICPRTR 4HR2 Chain:A ((5-145)) MALERTLSIIKPDAVAKNVIGQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVEFMISGPVMIQVLEGEDAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETARVEIAFFFPEMNVYSR--

General information: TITO was launched using: RESULT: Template: 4HR2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 668 -55445 -83.00 -393.23 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.91 3D Compatibility (PKB) : -83.00 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.91 QMean score : 0.450

(partial model without unconserved sides chains): PDB file : Tito_4HR2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HR2-query.scw PDB file : Tito_Scwrl_4HR2.pdb: