Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MERYTVMGQLGDGSFGTVSKAQNTSTGEIVAVKKMKQRFHSWEECL-QLREIQSLRKVQHPNLVKLKEVVREKTELFMIFEYCEKNIFQIQRQRANEMSGTMAFSDKEIRSIMCQTLLGVQAIHKAGFMHRDLKPENLLISGD---LVKVADFGLAKE-IRSRPPFTEYVSTRWYRAPELVLHSTHYNSPVDIWACAVIFAELYLCRPLFPGTSESDQLFKICSVLGSPAPNEWDEGYQLARRMNMRFPTVAPTPLRHIL-TTAPPAAVDLMAQMLRFNPAERPTATQCLQHPYFTGSGGSSALYAGIATGQPHNPFQLAASSAVAAQSMSNVGLTSNSSPPPTTSNASLFKYANLFNQGNRSPLSVSSTSAPFSGSSALQGSVTSSNMVRSVPTQRKTSVPNAVDSDDEFNF 3GC0 Chain:A ((33-323)) IDRYRRITKLGEGTYGEVYKAIDTVTNETVAIKRI--RLEH-----TAIREVSLLKELQHRNIIELKSVIHHNHRLHLIFEYAENDL-------KKYMDKNPDVSMRVIKSFLYQLINGVNFCHSRRCLHRDLKPQNLLLSV-ETPVLKIGDFGLARAF---------EIITLWYRPPEILLGSRHYSTSVDIWSIACIWAEMLMKTPLFPGDSEIDQLFKIFEVLGLPDDTTW-PGVTALPDWKQSFPKFRGKTLKRVLGALLDDEGLDLLTAMLEMDPVKRISAKNALEHPYFS---------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3GC0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1331 -33400 -25.09 -126.04 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -25.09 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_3GC0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GC0-query.scw PDB file : Tito_Scwrl_3GC0.pdb: