Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAEVLHHDNHGHDGHHEHDDTDLTVFGFWTYLMSDLILFGSLFIAFAVLSSHVPPGTPSAYDLFHES-------LGYVLTETFALLISSVTFGFAVLASYKKNVNQVITWLFITFLFGATFIGMELYEFHHLVEEGHGPTHSAFLSSFFTLVGTHGIHVTSGLVWMLVLMYQIKTKGLTLPNTRRLACLSLFWHFLDIVWICVFSVVYLLGVL 3ABL Chain:C ((68-260)) ------------QGHHTPAVQKGLRYGMILFIISEVLFFTGFFWAF-YHSSLAP--TPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGDRKHMLQALFITITLGVYFTLLQASEYY---EAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWG--

General information: TITO was launched using: RESULT: Template: 3ABL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 654 -82328 -125.88 -442.62 target 2D structure prediction score : 0.80 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -125.88 2D Compatibility (Sec. Struct. Predict.) : 0.80 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.409

(partial model without unconserved sides chains): PDB file : Tito_3ABL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ABL-query.scw PDB file : Tito_Scwrl_3ABL.pdb: