Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYSIGQVSEMFGLPVSTLRYYDKEGLF------PDIQRVSGIRKFSENELEALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELF----EKQKEVVEKE--IAKLERVLAMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH 3Q1M Chain:A ((6-108)) -YSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPD----TSYRYYTDSQLIHLDLIKSLKYIGTPLEEMKKAQDLEME---------ELFAFYTEQERQIREKLDFLSALEQTISLV---------------------------------------

General information: TITO was launched using: RESULT: Template: 3Q1M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 253 -13419 -53.04 -147.46 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -53.04 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.643

(partial model without unconserved sides chains): PDB file : Tito_3Q1M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q1M-query.scw PDB file : Tito_Scwrl_3Q1M.pdb: