Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence FCVYYDGHLPATRVLLMYVRIGTTATITA----------------RGHEFEVEAK-DQNCKVILTNGKQAPDWLAAEPY 4GUL Chain:A ((185-245)) ---------PKGWTSFIYTISGD-VYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVLIAGEPLR--------

General information: TITO was launched using: RESULT: Template: 4GUL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 113 1397 12.36 31.75 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 12.36 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.507

(partial model without unconserved sides chains): PDB file : Tito_4GUL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GUL-query.scw PDB file : Tito_Scwrl_4GUL.pdb: