Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MSRSVLQPSQQKLAEKLTILNDRGVGMLTRLYNI-KKACGDPKAKPSYLIDKNLESAVKFIVRKFPAVETRNNNQQLAQLQKEKSEILKNLALYYFTFVDVMEFKDHVCELLNTIDVCQVFFDITVNFDLTKNYLDLIITYTTLMILLSRIEERKAIIGLYNYA----HEMTHGASDREYPRLGQMIVDYENPLKKMMEEFVPHSKSL-SDALISLQMVYPRRNLSA----------DQWRNAQLLSLISAPSTMLN---------PAQSDTMPCEYLSLDAMEKWIIFGFILCHGILNTDATALNLWKLALQSSSCLSLFRDEVFHIHKAAEDLFVNI-RGYNKRINDIRECKEAAVSHAGSMHRERRKFLRSALKELATVLSDQPGLLGPKALFVFMALSFARDEIIWLLRHADN--MPKKSADDFIDKHIAELIFYMEELRAHVRKYGPVM------QRYYVQYLSGFDAVVLNELVQNLSVCPEDESIIMSSFVNTMTSLSVKQVEDGEVFDFRGMRLDWFRLQAYTSVSKASLGLADHRELGKMMNTIIFHTKMVDSLVEMLVETSDLSIFCFYSRAFEKMFQQC--------LELPSQSRYSIAFPLLCTHFMSCTH------ELCPEERHHIGDRSLSLCNMFLDEMAKQARNLITDICTEQCTLSDQLLPKHCAKTIS-QAVNKKSKKQTGKKGEPEREKPGVESMRKNRLVVTN-----------LDKLHTALSELCFSINYVPNMVVWEHTFT----------PREYLTSHLEIRFTKSIVGMTMYNQATQEIAKPSEL--LTSVRAYMTVLQSIENYVQIDITRVFNNVLLQQTQHLDSHGEPTITSLYTNWYLETL-------LRQVSNGHIAYFPAMKAFVNLP----TENELTFNAEEYSDISEMRSLSE--LLGPYGMKFLSESLMWHISSQVAELKKLVVENVDVLTQMRTSFDKPDQMAALFKRLSSVDSVLKRMTIIGVILSFRSLAQEALRDVLSYHIPFLVSSIEDFKDHIPRE-TDMKVAMNVYELSSAAGLPCEIDPALVVALSSQKSENISPEEEYKIACLLMVFVAVSLPTLASNVMSQYSPAIEGHCNNIHCLAKAINQIAAALFTIHKGSIEDRLKEFLALASSSLLKIGQETDKTTTRNRESVYLLLDMIVQESPFLTMDLLESCFPYVLLRNAYHAVYKQSVTSSA 4CMP Chain:A ((8-1367)) KYSIGLDIGT-----------NSVGWAVITDEYKVPSKKFKVLGNTDRHSIKKNLIGALLF-----DSGETAEATRLKRTARRRYTRRKNRICYLQEIFSNEMAKVDD--SFFHRLERHPIFGNIVDEVAYHEKYPTIYHLRKKLVDSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDVDKLFIQLVQTYNQLFEENPINASGVDAKAILSARLSKSRRLENLIAQLPGEKKNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMD----------GTEELLVKLN----REDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRPNEKVLPKHSLLYEYFTVYNELTKVLS--GEQKKAIVDLLFKTNRKVTVKQLKE----DFNASLGTYHDLLKIIK----DKDFLDNEENEDILEDIVLTLTLFED-REMIEERLKTYAHLFDDKVMKQLKRRRYTGWGRLSRKLINGIRDKTILDFLKRNFMQLIHDDSLTFKEDIQKAQVSDSLHEHIANLAGSPAIKKGILQTVKVVDELVKVMGRHKPENIVIEMAKNSRERMKRIEEGIKELHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFLKDDSIDNKVLTRKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYPKLESEFVYGDYKVYDVRKMIAKSEQYFFYSNIMNFFKTEIT--LANGEIRKRPLIETNGE---TGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTPTVAYSVLVVSVKELLGITIMERSSFEKNPIDFLEAKGKDLIIKLPKY-------SLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHYVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENIIHLFTLTNL------------GAPAAFKYFDTTIDRKRYTSTKEVLDA---TLIHQSITGLYETRIDLS-

General information: TITO was launched using: RESULT: Template: 4CMP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 4854 132647 27.33 125.49 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 27.33 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.221

(partial model without unconserved sides chains): PDB file : Tito_4CMP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CMP-query.scw PDB file : Tito_Scwrl_4CMP.pdb: