Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEKEIFDRIVTIIQERQG-EDFVVTESLSLKDDLDADSVDLMEFILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK 3EJD Chain:A ((23-95)) -----IEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGH

General information: TITO was launched using: RESULT: Template: 3EJD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 236 8909 37.75 123.73 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : 37.75 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.547

(partial model without unconserved sides chains): PDB file : Tito_3EJD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EJD-query.scw PDB file : Tito_Scwrl_3EJD.pdb: